Monday, November 12, 2012

Nutritional Effects and Safety Issues of Olestra

The Procter and Gamble Company filed a petition with the FDA in 1999, proposing that the label statement be upstage regarding food additive regulations. Procter and Gamble contend that scientific yard collected since 1996 shows that the label is inaccurate, with incomplete information, and misunderstood by customers (FDA, 2000).

Olestra is not toxic. It is not considered to be carcinogenic, genotoxic, or teratogenic. It is nondigestable and is not absorbed or metabolized by the be, and it does not affect the absorption of water-soluble vitamins (Prince & Welschenbach, p. 565).

Olestra interacts with the body in the lumen of the gut and does not involve the alimentary digestion, absorption, or metabolism processes. It does not effect nutrient stores that were accumulated prior to its consumption, therefore it does not deplete the body of nutrients (Peters, Lawson, Middleton, & Triebwasser, 1997, p. 1719S).

increase amounts of people of all ages ar found to exceed their optimum body weight. Diets high in voluptuous and obesity ar associated to many health problems much(prenominal) as cardiovascular disease, cancer, diabetes, and arthritis. Since olestra is fat free, it offers a transfigure for fat, and has a palatable flavor and texture. Olestra molecules be too big to be absorbed intact since they ar not hydrolyzed, they pass through the body in an same(predicate) form, providing no calories (Doyle, 1997, pp. 370-371).


Josefson, D. (1998). Fat substitute declared safe. British Medical Journal, 316(7149), 1926.

Although the degree that the population suffers from these symptoms clay controversial, olestra may cause gastrointestinal tract symptoms to complicate cramping or loose stools.
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Procter and Gamble report results of a 5 calendar month trial that included 3,357 subjects; well-nigh reported gastrointestinal disturbances to include ulcerative colitis and two reported gastrointestinal disturbances with or without olestra. The data is insufficient to form valid conclusions and many are concerned regarding a more widespread use of olestra (Doyle, p. 371).

Olestra is as well as not a pollution threat to the environment. Microorganisms in soils and sewage sludges are able to utilize olestra from discarded waste such as potato chips, as a sole parentage of carbon and energy (Doyle, pp. 370-371).

Bonn, D. (1996). FDA requested to rescind olestra. The Lancet, 348(9026), 539.

Another mischief to olestra, may be anal leakage of olestra in some subjects. Early trials found that undigested olestra passed through the body via the digestive track and then arrived as a transparent muss at the anal sphincter. This muscle could not contain the liquid mass and leakage occurred. Efforts were made to eliminate this problem by adding longerchain and highly saturated fatty acids, to reformulate olestra, which now carcass stiffer at body temperatures (Doyle, p. 371).


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